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PANRE test Format | PANRE Course Contents | PANRE Course Outline | PANRE test Syllabus | PANRE test Objectives

Exam Code: PANRE

Exam Name: NCCPA PANRE Physician Assistant National Recertifying Exam

Total Number of Questions: 240 multiple-choice questions

Exam Structure: Divided into four blocks of 60 questions each.

Time Allotted: 4 hours total (60 minutes per block)

Passing Score: The NCCPA uses a scaled score (ranging from 200 to 800) based on standard setting by PAs. The minimum passing scaled score is typically 379.



1. Cardiovascular System 13%



- Hypertension (essential, secondary, hypertensive emergency)

- Coronary artery disease / Acute coronary syndromes (STEMI, NSTEMI, unstable angina)

- Heart failure (systolic, diastolic, right-sided, acute decompensated)

- Valvular disorders (mitral stenosis/regurgitation, aortic stenosis/regurgitation, tricuspid regurgitation, pulmonic stenosis)

- Cardiomyopathies (dilated, hypertrophic, restrictive, peripartum)

- Pericardial diseases (pericarditis, pericardial effusion, tamponade)

- Arrhythmias (atrial fibrillation/flutter, SVT, ventricular tachycardia/fibrillation, bradycardias, heart block)

- Conduction disorders (1st, 2nd, 3rd degree AV block, bundle branch blocks)

- Congenital heart disease (ASD, VSD, PDA, tetralogy of Fallot, coarctation – adult presentation)

- Peripheral vascular disease (PAD, venous thrombosis, varicose veins, chronic venous insufficiency)

- Aortic disease (aneurysm, dissection)

- Shock (cardiogenic, hypovolemic, distributive)

- Syncope

- Dyslipidemia



2. Pulmonary System 10%



- Asthma (including occupational and exercise-induced)

- Chronic obstructive pulmonary disease (chronic bronchitis, emphysema)

- Acute/chronic bronchitis and bronchiolitis

- Pneumonia (community-acquired, healthcare-associated, aspiration, viral, fungal)

- Pulmonary embolism and deep vein thrombosis

- Lung cancer (small cell, non-small cell, solitary pulmonary nodule)

- Pleural diseases (pleural effusion, pneumothorax, hemothorax)

- Pulmonary hypertension

- Interstitial lung disease / Pulmonary fibrosis

- Obstructive sleep apnea

- Acute respiratory distress syndrome (ARDS)

- Sarcoidosis

- Occupational lung diseases (asbestosis, silicosis, coal workers pneumoconiosis)

- Cystic fibrosis (adult presentation)



3. Gastrointestinal System / Nutrition 9%



- Esophageal disorders (GERD, esophagitis, Barrett esophagus, motility disorders, strictures)

- Gastric disorders (peptic ulcer disease, gastritis, H. pylori, Zollinger-Ellison)

- Gallbladder and biliary disease (cholecystitis, cholelithiasis, cholangitis, biliary dyskinesia)

- Liver diseases (acute/chronic hepatitis, cirrhosis, alcoholic liver disease, NAFLD/NASH, portal hypertension, esophageal varices)

- Pancreatic disorders (acute and chronic pancreatitis, pancreatic insufficiency)

- Small intestine (malabsorption syndromes, celiac disease, Crohns disease, small bowel obstruction)

- Large intestine (ulcerative colitis, diverticulitis, appendicitis, ischemic colitis, C. difficile colitis)

- Colorectal cancer and screening

- Constipation and diarrhea (acute/chronic)

- GI bleeding (upper and lower)

- Hernias (inguinal, umbilical, incisional)

- Anorectal disorders (hemorrhoids, anal fissure, abscess, fistula)

- Nutrition (malnutrition, obesity, vitamin/mineral deficiencies)



4. Musculoskeletal System 8%



- Osteoarthritis and degenerative joint disease

- Rheumatoid arthritis

- Crystal-induced arthropathies (gout, pseudogout)

- Seronegative spondyloarthropathies (ankylosing spondylitis, psoriatic arthritis, reactive arthritis)

- Systemic lupus erythematosus and connective tissue diseases

- Osteoporosis and osteopenia

- Fractures and dislocations (common sites: hip, wrist, ankle, stress fractures)

- Sprains, strains, and overuse syndromes (rotator cuff, lateral/medial epicondylitis, plantar fasciitis)

- Low back pain (disc herniation, spinal stenosis, sciatica, cauda equina)

- Pediatric orthopedics (scoliosis, Osgood-Schlatter, slipped capital femoral epiphysis)

- Compartment syndrome

- Septic arthritis and osteomyelitis



5. EENT (Eyes, Ears, Nose, Throat) 7%



- Conjunctivitis, keratitis, corneal abrasion/ulcer

- Glaucoma (open-angle, acute angle-closure)

- Cataract, macular degeneration, diabetic retinopathy

- Retinal detachment, retinal vascular occlusion

- Otitis media, otitis externa, cerumen impaction

- Hearing loss (conductive vs sensorineural)

- Sinusitis (acute/chronic), allergic rhinitis

- Epistaxis

- Pharyngitis/tonsillitis, peritonsillar abscess

- Oral leukoplakia, oral cancer, salivary gland disorders

- Vertigo (BPPV, vestibular neuritis, Ménière disease)



6. Reproductive System (Female) 5% & Genitourinary System (Male and Female) 5%



- Menstrual disorders (amenorrhea, abnormal uterine bleeding, dysmenorrhea)

- Menopause and hormone replacement

- Breast diseases (fibrocystic changes, mastitis, breast cancer screening, fibroadenoma)

- Pelvic inflammatory disease, endometritis

- Cervical dysplasia and cancer screening

- Contraception and family planning

- Vaginitis (bacterial vaginosis, candida, trichomoniasis)

- Endometriosis, adenomyosis, uterine leiomyoma

- Polycystic ovarian syndrome

- Benign and malignant ovarian tumors

- Prostate disorders (BPH, prostatitis, prostate cancer)

- Erectile dysfunction

- Testicular torsion, epididymitis, orchitis

- Urinary incontinence (stress, urge, overflow)

- Urologic cancers (bladder, renal cell, testicular)



7. Endocrine System 5%



- Diabetes mellitus (Type 1, Type 2, gestational, complications: DKA, HHS)

- Thyroid disorders (hypothyroidism, hyperthyroidism, thyroiditis, nodules, cancer)

- Adrenal disorders (Addison disease, Cushing syndrome, pheochromocytoma)

- Pituitary disorders (diabetes insipidus, acromegaly, hypopituitarism)

- Parathyroid disorders (hyper/hypocalcemia, hyperparathyroidism)

- Metabolic syndrome

- Dyslipidemia (already listed under CV but tested again here)



8. Neurology 5%



- Headache (migraine, tension, cluster, secondary causes)

- Seizure disorders and epilepsy

- Stroke (ischemic, hemorrhagic, TIA)

- Dementia (Alzheimer, vascular, Lewy body)

- Parkinson disease and movement disorders

- Multiple sclerosis

- Peripheral neuropathy (diabetic, B12 deficiency, Guillain-Barré)

- Myasthenia gravis and neuromuscular junction disorders

- Meningitis and encephalitis

- Brain tumors and metastases



9. Psychiatry / Behavioral Health 5%



- Mood disorders (depression, bipolar disorder, dysthymia)

- Anxiety disorders (GAD, panic disorder, PTSD, OCD)

- Psychotic disorders (schizophrenia, schizoaffective)

- Substance use disorders (alcohol, opioid, stimulant, cannabis)

- ADHD (adult presentation)

- Eating disorders (anorexia, bulimia)

- Personality disorders

- Suicide risk exam

- Somatoform and factitious disorders



10. Dermatology 5%



- Bacterial infections (impetigo, cellulitis, folliculitis, MRSA)

- Viral infections (herpes simplex, zoster, warts, molluscum)

- Fungal infections (tinea, candida, onychomycosis)

- Parasitic (scabies, lice)

- Acne, rosacea, hidradenitis suppurativa

- Psoriasis, lichen planus

- Eczema (atopic, contact, seborrheic)

- Urticaria and angioedema

- Drug eruptions

- Bullous diseases (pemphigus, bullous pemphigoid)

- Skin cancer (basal cell, squamous cell, melanoma, actinic keratosis)



11. Infectious Diseases 5%



- Sepsis and septic shock

- HIV/AIDS and opportunistic infections

- Tuberculosis and latent TB

- Sexually transmitted infections (gonorrhea, chlamydia, syphilis, herpes, HPV)

- Tick-borne diseases (Lyme, Rocky Mountain spotted fever, ehrlichiosis)

- Viral hepatitis (A, B, C)

- Osteomyelitis

- Endocarditis (native valve, prosthetic valve, culture-negative)

- Fever of unknown origin



12. Hematology 3%



- Anemias (iron deficiency, B12/folate deficiency, hemolytic, aplastic)

- Thrombocytopenia (ITP, TTP, HIT)

- Coagulopathies (hemophilia, von Willebrand, acquired)

- Leukemia (ALL, CLL, AML, CML)

- Lymphoma (Hodgkin, non-Hodgkin)

- Multiple myeloma and plasma cell disorders

- Transfusion reactions



13. Renal System 3%



- Acute kidney injury

- Chronic kidney disease and ESRD

- Glomerulonephritis and nephrotic syndrome

- Electrolyte disturbances (hyponatremia, hyperkalemia, etc.)

- Acid-base disorders

- Nephrolithiasis

- Pyelonephritis and urinary tract infections

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